Intestinal permeability of antivirus constituents from the fruits of Eucalyptus globulus Labill. in Caco-2 Cell Model

X Yang, Q Guo, Y Wang, W Xu, L Tian, X Tian - Bioorganic & medicinal …, 2007 - Elsevier
The uptake and transepithelial transport of the three main constituents macrocarpal A (MA),
macrocarpal B (MB), and cypellocarpa C (Cy-C) from the fruits of Eucalyptus globulus Labill.
were investigated. Monolayers of the human intestinal epithelial cancer cell line Caco-2
were incubated with MA, MB, and Cy-C to model its intestinal absorption and transport,
respectively. The determination of compounds was performed by HPLC. The apparent
permeability coefficients (Papp) for MA, MB, and Cy-C in the apical-to-basolateral direction …
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